2018.09 -                   福州大学化学学院                    研究员

2010.11－2018. 08   福州大学化学学院                     副研究员

2008.08－2010.10    香港中文大学化学系                 博士后

2005.08－2008.07    香港中文大学化学系                 化学 博士

2002.09－2005.07    厦门大学化学化工学院             无机化学 硕士  

1998.09－2002.07    江西师范大学化学化工学院      化学教育   学士

承担本科生课程：  《有机化学》  《综合实验》  《有机化学实验》
承担研究生课程：   《现代有机化学合成》 《实验室安全讲座》   《有机化学研究方法》

研究兴趣：

氟硼二吡咯、酞菁类抗癌光敏药物的设计与药效研究；  
  有机染料分子荧光探针的设计及其在细胞、活体肿瘤中的成像研究；  
  染料敏化太阳能电池材料的设计及其光电转换性能研究；  
  酞菁和氟硼二吡咯的超分子化学。

中国化学会应用化学学科委员会卟啉与酞菁专业委员会秘书

担任Chemical   Communications, Journal of Medicinal Chemistry, Green Chemistry, Chemistry A   European Journal, Organic Letters, RSC Advances, ChemMedChem, Current   Medicinal Chemistry等期刊的通讯审稿人。

1.国家自然科学基金（面上），生物素介导靶向光动力治疗-化疗联用抗癌药物的合成及构效关系研究 (No.21401733)，2015.1-2018.12，主持，在研 

2.福建省科技厅重大项目，抗癌光敏剂福大赛因临床Ⅱ期人体药代动力学研究（No.2015Y0086）2015.11-2018.10，主持，在研

3.国家自然科学基金（青年），叶酸-酞菁共轭物抗癌光敏剂的合成及其靶向光动力活性研究 (No.21101028)，2012.1-2014.12，主持，结题

4.福建省自然科学基金（青年创新），Cu（I）催化“点击化学”合成靶向抗癌光敏剂   (No.2012J05021)，2012.1-2014.12，主持，结题

5.福州大学海外人才引进项目，功能配合物 (No.022382)，2012.1-2014.12，主持，结题

6.福州大学科研启动项目，靶向抗癌光敏剂的研究 (No.600366)，2012.1-2014.12，主持，结题

7.福州大学科技发展基金，分子靶点抗癌光敏剂 (No.2011-XY-6) ，2013.1-2015.12，主持，结题

2.Zhang, F.-L.; Song, M.-R.; Yuan, G.-K.; Ye, H.-N.; Tian, Y.; Huang, M.-D.; Xue, J.-P.; Zhang, Z.-H.*; Liu, J.-Y.* “A Molecular Combo of Zinc(II)   Phthalocyanine and Tamoxifen Derivative for Dual Targeting Photodynamic   Therapy and Hormone Therapy”J.   Med. Chem., 2017, 60,   6693-6703.

3.Liu J.-Y*; Wang, C.; Zhu,   C.-H.; Zhang, Z.-H.*; Xue, J.-P.   “Preparation and In Vitro Photodynamic Activity of Glucosylated Zinc(II)   Phthalocyanines as Underlying Targeting Photosensitizers”, Molecules 2017, 22, 845-857.

4.Liu, J.-Y.*; Hou,   X.-N.; Tian, Y.; Jiang, L.*; Deng, S.; Röder, B.;   Ermilov, E. A.* “Photoinduced energy and charge transfer in a   bis(triphenylamine)–BODIPY–C₆₀ artificial photosynthetic system”, RSC Advances, 2016, 6, 57293-57305.

5.Liu,   J.-Y.; Li,   J.; Yuan, X.; Wang, W.-M.; Xue, J.-P.* “In vitro photodynamic   activities of zinc(II) phthalocyanines substituted with pyridine moieties”, Photodiagnosis and Photodynamic Therapy,   2016, 13, 341-343.

6.Chen, J.;   Ye, H.; Zhang, M.; Li, J.; Liu, J.-Y.*; Xue, J.-P.* “Erlotinib Analogue-substituted Zinc(II)   Phthalocyanines for Small Molecular Target-based Photodynamic Cancer   Therapy”, Chin. J. Chem., 2016, 34, 983-988.

7.Ermilov, E. A. *; Liu, J.-Y.; Menting, R.; Huang, Y.-S.; Röder,   B.; Ng, D. K. P.* “An artificial   photosynthetic model based on a molecular triad of boron dipyrromethene and   phthalocyanine” Phys. Chem. Chem. Phys., 2016, 18,   10964-10975.

8.Zhang, F.-L.; Huang, Q.; Liu,   J.-Y.; Huang, M.-D.; Xue, J.-P.* “Molecular-Target-Based   Anticancer Photosensitizer: Synthesis and in vitro Photodynamic Activity of   Erlotinib–Zinc(II)Phthalocyanine Conjugates” ChemMedChem, 2015, 10(2), 312-320.

9.Ermilov, E. A.*; Schlak, M.; Steffen, R.; Liu, X.-Q.; Liu, J.-Y.; Röder, B. “Energy transfer   properties of a novel boron dipyrromethene–perylenediimide donor–acceptor   dyad” RSC Adv., 2015, 5, 67141-67148.

10.Zhou, X.-Q.; Meng, L.-B.; Huang, Q.; Li, J.; Zheng, K.; Zhang, F.-L.; Liu,   J.-Y.; Xue, J.-P.* “Synthesis and in vitro Anticancer Activity of Zinc(II) Phthalocyanines   Conjugated with Coumarin Derivatives for Dual Photodynamic and Chemotherapy” ChemMedChem, 2015, 10, 304-311.

11.Lin,   J.; Zhu, C.; Liu, X.; Chen, B.; Zhang, Y.; Xue, J.;Liu, J.-Y.* “A Highly   Selective and turn-on fluorescence probe for Fe³⁺ ion based on perylene tetracarboxylic diimide” Chin.   J. Chem., 2014, 32, 1116-1120.

12.Jia, X.;   Yue, F.; Chen, X.; Pan, H.-B.; Liu, W.-G.*; Liu, J.-Y.* “One-pot controlled synthesis of single-crystal a-Fe₂O₃   hollow nanostructure and its gas sensing properties” RSC Adv., 2014, 4, 42899-42904.

13.Liu,   J.-Y.; Huang, Y.-S.; Menting, R.; Röder, B.; Ermilov, E. A.; Ng, D. K. P.* “A   boron dipyrromethene-phthalocyanine pentad as an artificial photosynthetic   model” Chem.   Commun. 2013, 49, 2998-3000.

14.Liu, J.-Y.; Ermilov, E. A.; Röder, B.; Ng, D. K. P.* “A   light-harvesting porphyrin-boron dipyrromethene conjugate” J.   Porphyrins Phthalocyanines 2013, 17, 831-835.

15.Menting,   R.;Liu, J.-Y.;Huang, Y.-S.;Ng, D.   K. P.;Röder, B.;Ermilov,   E. A.* “Photoinduced   energy and charge transfer in a p-phenylene-linked   dyad of boron dipyrromethene and monostyryl boron dipyrromethene” Phys. Chem. Chem. Phys. 2013, 15, 6912-6919.

16.Zhang,   F.-L.; Huang, Q.; Zheng, K.; Li, J.;Liu, J.-Y.*; Xue, J.-P.* “A novel strategy   for targeting photodynamic therapy. Molecular combo of photodynamic agent   zinc(II) phthalocyanine and small molecule target-based anticancer drug   erlotinib” Chem. Commun. 2013, 49, 9570-9572.

17.Jia,   X.; Yang, F.-F.; Li, J.; Liu, J.-Y.; Xue, J.-P.*“Synthesis and in Vitro Photodynamic   Activity of Oligomeric Ethylene Glycol−Quinoline Substituted Zinc(II) Phthalocyanine   Derivatives” J. Med. Chem.   2013, 56, 5797-5805.

18.He,   H.; Liu, J.-Y.; and Ng,   D. K. P.* “A Phthalocyanine-Based Fluorescent Sensor for Zn²⁺   Ion”, J. Porphyrins Phthalocyanines”   2013, 17, 99-103.

19.Liu, J.-Y.; El-Khouly, M. E.; Fukuzumi, S.; Ng, D. K. P.* “Photoinduced   Electron Transfer in a Ferrocene-Distyryl BODIPY Dyad and a   Ferrocene-Distyryl BODIPY-C₆₀ Triad” ChemPhysChem, 2012, 13, 2030-2036.

20.Shi, W.-J.; Liu, J.-Y.; Ng, D. K. P.* “A   Highly Selective Colorimetric and Fluorescent Probe for Cu²⁺ and   Hg²⁺ Ions Based on a Distyryl BODIPY with Two   Bis(1,2,3-triazole)amino Receptors”   Chem. Asian. J. 2012,7(1), 196-200.

21.Liu, J.-Y.; El-Khouly, M. E.; Fukuzumi, S.*; Ng, D. K. P.* “Mimicking   the Photosynthetic Antenna-Reaction Center Complexes with a (Boron   Dipyrromethene)₃-Porphyrin-C₆₀ Pentad”Chem. Eur. J. 2011,17, 1605-1613.

22.Liu, J.-Y.; El-Khouly, M. E.; Fukuzumi, S.; Ng, D. K. P.* “Photoinduced   Electron Transfer in a Distyryl BODIPY-Fullerene Dyad” Chem. Asian. J. 2011,6, 174-179.

23.Liu, J.-Y.; Lo, P.-C.; Ng, D. K. P.*   “Phthalocyanine-Containing Supramolecular Arrays” Struct. Bond. 2010, 135, 169-210.

24.Liu, J.-Y.; Ermilov, E. A.; Röder, B.; Ng, D. K. P.* “Switching   the photo-induced energy and electron-transfer processes in   BODIPY-phthalocyanine conjugates” Chem. Commun. 2009, 45, 1517-1519.

25.Liu, J.-Y.; Lo, P.-C.; Jiang, X.-J.; Fong, W.-P.; Ng, D. K. P.*   “Synthesis   and in vitro photodynamic activities of di--substituted zinc(II)   phthalocyanine derivatives” Dalton Trans. 2009, 38, 4129-4135.

26.Liu, J.-Y.; Lo, P.-C.; Fong, W.-P.; Ng, D. K. P.* “Effects of   the number and position of the substituents on the in vitro photodynamic   activities of glucosylated zinc(II) phthalocyanines” Org.   Biomol. Chem. 2009, 7, 1583-1591.

27.Ermilov, E. A.*; Liu, J.-Y.; Ng, D. K. P.*; Röder, B.   “Spectroscopic study of electron and energy transfer in novel silicon   phthalocyanine-boron dipyrromethene triads” Phys. Chem. Chem. Phys. 2009,   11, 6430-6440.

28.Liu,   J.-Y.; Yeung, H.-S.; Xu, W.; Li, X.; Ng, D. K. P.*   “Highly Efficient Energy Transfer in Subphthalocyanine-BODIPY   Conjugates”   Org. Lett. 2008, 10(23), 5421-5424.

29.Liu, J.-Y.; Jiang, X.-J.; Fong, W.-P.; Ng, D. K. P.* “Highly   photocytotoxic 1,4-dipegylated zinc(II) phthalocyanines.  Effects of the chain length on the in vitro   photodynamic activities”   Org. Biomol. Chem. 2008,   6, 4560-4566.

30.Liu, J.-Y.; Jiang, X.-J.; Fong, W.-P.; Ng, D. K. P.* “Synthesis,   Characterization, and in vitro Photodynamic Activities of Novel Amphiphilic Zinc(II)   Phthalocyanines Bearing Oxyethylene-rich Substituents” Metal Based Drugs 2008, Article ID: 284691.

31.Lo, P.-C.;   Chan, C. M. H.;Liu, J.-Y.; Fong,   W.-P.; Ng, D. K.-P.* “Highly Photocytotoxic Glucosylated Silicon(IV)   Phthalocyanines. Effects of Peripheral Chloro Substitution on the   Photophysical and Photodynamic Properties” J. Med.   Chem. 2007, 50(9), 2100-2107.

福州大学学术新人奖，香港福慧奖学金

申请发明专利12项，已授权8项